Category: Medicine

What is Thalassemia? Thalassemia is a heterogeneous group of hemoglobinopathies, which are based on a decrease in the synthesis of polypeptide chains that are part of the structure of normal hemoglobin A. Thalassemia is target-cell

What is Pro-lymphocytic Leukemia? Pro-lymphocytic leukemia is a variant of chronic lymphocytic leukemia with larger and less differentiated cells. Pathogenesis during Pro-lymphocytic Leukemia The following variants of prolymphocytic leukemia are distinguished: The B-cell variant is

What is Porphyria? The first cases of porphyria were described in 1874 by the scientist Schultz. The patient from early childhood had an increased sensitivity to solar radiation, an enlarged spleen, and red urine. A

What is Plasma Cell Acute Leukemia? Plasma cell acute leukemia, according to the literature, is a rare variant of leukemia. This disease, like B-cell acute leukemia, according to modern concepts of hematopoiesis should belong to

What are Individual Forms of Leukemia? The two leukemia described above have histochemical differences; however, their morphology and clinical picture are almost the same. Myelomonoblastic acute leukemia can be represented by cells, each of which

What is Acute Promyelocytic Leukemia? Acute promyelocytic leukemia – OPL (MOH according to the FAB classification) is a rather rare variant of acute leukemia, it accounts for no more than 10% of all acute non-lymphoblastic

What is Acute Post-Hemorrhagic Anemia? Acute post-hemorrhagic anemia is understood as anemia that has developed as a result of the rapid loss of a significant amount of blood. In the mechanism of development of the

What is Hereditary Spherocytosis (Minkowski-Chauffard Disease)? Hereditary spherocytosis (Minkowski-Chauffard disease) – hemolytic anemia due to a defect in the cell membrane of erythrocytes, the permeability of the membrane to sodium ions becomes excessive, and therefore

What is Hereditary Microspherocytosis? Hereditary microspherocytosis, also known as Minkowski – Chauffard disease, is a hereditarily determinable disease transmitted by an autosomal dominant type, characterized by a defect in the erythrocyte membrane proteins. As a

What is a Violation of Coagulation Hemostasis? This group includes genetically determined hypocoagulations, characterized by a deficiency, as well as molecular abnormalities of blood coagulation factors. Thus, 83-90% of all hereditary bleeding disorders are 2