What is the Bug Origin of Hemoblastosis?
Leukemia cells are a clone, that is, the offspring of a single mutated cell, and carry the characteristics of an originally mutated cell.
Chromosomal analysis of acute leukemias that have arisen in patients with erythremia treated with radioactive phosphorus has shown in some cases unambiguous specific chromosomal changes in tumor cells. This is a direct result.
radiation exposure and evidence of the mutational nature of these forms of acute leukemia, their origin from a single cell.
When secreting lymphocytomas, lymphosarcomas, multiple myeloma, Waldenstrom macroglobulinemia – hemoblastosis, arising in the system of lymphatic and plasma cells, a sharp increase in any single immunoglobulin is detected. This fact indicates the homogeneity of tumor cells in each such case by protein synthesis and their origin from a single cell.
In chronic lymphocytic leukemia, the leukemic cells of the same type are also identified in each specific case in terms of cytoplasmic and surface immunoglobulins.